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RN213 rabbit pAb

This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t (2;17) (p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t (8;17) (q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],

Product Specifications

Background

This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t (2;17) (p23; q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t (8;17) (q24; q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

Gene ID

57674

UniProt

Q63HN8

Cellular Locus

Cytoplasm, cytosol. Lipid droplet.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human RN213. AA range:307-407

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF

Validated Applications

IHC,IF

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1: 50-200

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES13369-1.pdf

Subcellular Location

Cytoplasm, cytosol . Lipid droplet .

Gene ID (Human)

57674

SwissProt (Human)

Q63HN8

Available Sizes

Curated Selection

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