N-Acetylneuraminate lyase (CgNal)

N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal) ) is a class I aldolase, is often used in biochemical studies. N-Acetylneuraminate lyase (CgNal) catalyzes the reversible condensation of pyruvate with N-acetyl-d-mannosamine (ManNAc) to yield the sialic acid N-acetylneuraminic acid (Neu5Ac) [1].

Product Specifications

CAS Number

[9027-60-5]

Product Name Alternative

Sialic acid aldolase (CgNal)

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-acetylneuraminate-lyase-cgnal.html

Solubility

10 mM in DMSO

Smiles

[N-Acetylneuraminatelyase(CgNal)]

References & Citations

[1]Daniels AD, et al. Reaction mechanism of N-acetylneuraminic acid lyase revealed by a combination of crystallography, QM/MM simulation, and mutagenesis. ACS Chem Biol. 2014 Apr 18;9 (4) :1025-32.