Hoechst 33342 analog
Hoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Product Specifications
CAS Number
[178481-68-0]
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hoechst-33342-analog.html
Purity
98.16
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(CCCC6=CC=C(N(CCCl)CCCl)C=C6)N5)=C4)N3)=C2)CC1
Molecular Formula
C32H37Cl2N7
Molecular Weight
590.59
Precautions
H302, H315, H319, H335
References & Citations
[1]Chazotte B. Labeling nuclear DNA with hoechst 33342. Cold Spring Harb Protoc. 2011 Jan 1;2011 (1) :pdb.prot5557.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
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