Xerophilusin B
Xerophilusin B, an anticancer agent isolated from Isodon xerophilus, exhibits antiproliferative effects on esophageal squamous cell carcinoma (ESCC) cell lines, induces G2/M cell cycle arrest, and mediates apoptosis[1].
Product Specifications
CAS Number
167894-15-7
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/xerophilusin-b.html
Solubility
10 mM in DMSO
Smiles
O[C@]12[C@]34[C@]5([H])[C@@]6(C(O[C@@]3([H])[C@](CC5)([H])C(C4=O)=C)([H])O2)[C@](C(C)(CCC6)C)([H])[C@@H]1O
Molecular Formula
C20H26O5
Molecular Weight
346.42
References & Citations
[1]Ran Yao, et al. Xerophilusin B induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma cells and does not cause toxicity in nude mice. J Nat Prod. 2015 Jan 23;78 (1) :10-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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