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Xerophilusin B

Xerophilusin B, an anticancer agent isolated from Isodon xerophilus, exhibits antiproliferative effects on esophageal squamous cell carcinoma (ESCC) cell lines, induces G2/M cell cycle arrest, and mediates apoptosis[1].

Product Specifications

CAS Number

167894-15-7

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/xerophilusin-b.html

Solubility

10 mM in DMSO

Smiles

O[C@]12[C@]34[C@]5([H])[C@@]6(C(O[C@@]3([H])[C@](CC5)([H])C(C4=O)=C)([H])O2)[C@](C(C)(CCC6)C)([H])[C@@H]1O

Molecular Formula

C20H26O5

Molecular Weight

346.42

References & Citations

[1]Ran Yao, et al. Xerophilusin B induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma cells and does not cause toxicity in nude mice. J Nat Prod. 2015 Jan 23;78 (1) :10-6.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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