SM-360320
SM-360320 (CL-087) is a potent, orally active TLR7 agonist. SM-360320 is a immuno-modulator and exerts an antitumor effect. SM-360320 can act in synergy with DNA vaccines leading to an enhanced Th1 antibody response[1]. SM-360320 can inhibit HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity[2].
Product Specifications
CAS Number
226907-52-4
Product Name Alternative
CL-087
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/sm-360320.html
Purity
99.41
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COCCOC1=NC(N)=C2C(N(C(N2)=O)CC3=CC=CC=C3)=N1
Molecular Formula
C15H17N5O3
Molecular Weight
315.33
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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