Alizarin Red S (sodium)

Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm[1][2][3][4][5].

Product Specifications

CAS Number

[130-22-3]

Product Name Alternative

ARS (sodium)

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/alizarin-red-s-sodium.html

Purity

95.0

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

O=S(C(C=C1C2=O)=C(O)C(O)=C1C(C3=C2C=CC=C3)=O)(O[Na])=O

Molecular Formula

C14H7NaO7S

Molecular Weight

342.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Soomin Lim, et al. Stimulatory Effects of KPR-A148 on Osteoblast Differentiation and Bone Regeneration. Tissue Eng Regen Med. 2019 Jul 17;16 (4) :405-413.|[2]H Paul, et al. Alizarin red S staining as a screening test to detect calcium compounds in synovial fluid. Arthritis Rheum. 1983 Feb;26 (2) :191-200.|[3]H Vilmann, et al. The in vivo staining of bone with alizarin red S. J Anat. 1969 Nov;105 (Pt 3) :533-45.|[4]W Querido, et al. Giemsa as a fluorescent dye for mineralizing bone-like nodules in vitro. Biomed Mater. 2012 Feb;7 (1) :011001.|[5]Bo Lai, et al. Application of excitation and emission matrix fluorescence (EEM) and UV-vis absorption to monitor the characteristics of Alizarin Red S (ARS) during electro-Fenton degradation process. Chemosphere.2013 Nov;93 (11) :2805-13.