Amine-PEG3-Lys (PEG3-N3) -PEG3-N3
Amine-PEG3-Lys (PEG3-N3) -PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2244602-35-3]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amine-peg3-lys-peg3-n3-peg3-n3.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCCOCCOCCOCCN=[N+]=[N-])[C@H](CCCCNC(COCCOCCOCCN=[N+]=[N-])=O)NC(COCCOCCOCCN)=O
Molecular Formula
C30H58N10O12
Molecular Weight
750.84
References & Citations
[1]Anami Y, et, al. Enzymatic conjugation using branched linkers for constructing homogeneous antibody-drug conjugates with high potency. Org Biomol Chem. 2017 Jul 5;15 (26) :5635-5642.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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