Resomelagon (acetate)
Product Specifications
UNSPSC Description
Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon acetate induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon acetate has anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research[1][2].
Target Antigen
Melanocortin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/resomelagon-acetate.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N=C(N)N/N=C/C=C/C1=CC=CN1C2=C(C=CC=C2)[N+]([O-])=O.CC(O)=O
Molecular Weight
358.35
References & Citations
[1]Montero-Melendez T, et, al. Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol. 2015 Apr 1;194(7):3381-8.|[2]WHO Drug Information. International Nonproprietary Names for Pharmaceutical.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147301A/Resomelagon-acetate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147301A/Resomelagon-acetate-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1809420-72-1
Available Sizes
Curated Selection
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