Anti-Cholera Toxin Beta Subunit Antibody

Mouse Monoclonal Antibody specific to Cholera toxin beta subunit

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Cholera enterotoxin B chain, Cholera enterotoxin γ chain, Choleragenoid

Gene Name

ctxB

NCBI Gene ID

UniProt

P01556

Cellular Locus

Secreted. Host cell membrane

Host

Mouse

Reactivity

Cholera Toxin Beta Subunit

Immunogen

Purified beta subunit of cholera toxin.

Target Antigen

Cholera enterotoxin subunit B

Target

Cholera Toxin Beta Subunit

Clonality

Monoclonal

Isotype

IgG1

Type

Antibody

Applications

ELISA, IHC

Field of Research

Infectious Disease

Purification Method

Purified by Protein A affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.

Additionnal Information

This antibody may be used for detection of cholera toxin in ELISA. Not all applications have been investigated.

Storage Conditions

These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Specificity

This antibody recognizes the beta subunit of cholera toxin and does not cross-react with the alpha subunit, however it cross-reacts with E. coli heat labile enterotoxin.