(2-Chloropyridin-4-yl) methanamine hydrochloride
(2-Chloropyridin-4-yl) methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM.
Product Specifications
CAS Number
[916210-98-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/LOXL2-IN-1_hydrochloride.html
Concentration
10mM
Purity
99.70
Solubility
DMSO : 87.5 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
[H]Cl.ClC1=NC=CC(CN)=C1
Molecular Formula
C6H8Cl2N2
Molecular Weight
179.05
Precautions
H302, H315, H319, H335
References & Citations
[1]Hutchinson JH, et al. Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX. ACS Med Chem Lett. 2017 Mar 1;8 (4) :423-427.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
