(2-Chloropyridin-4-yl) methanamine hydrochloride
(2-Chloropyridin-4-yl) methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM.
Product Specifications
CAS Number
916210-98-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/LOXL2-IN-1_hydrochloride.html
Concentration
10mM
Purity
99.70
Solubility
DMSO : 87.5 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
[H]Cl.ClC1=NC=CC(CN)=C1
Molecular Formula
C6H8Cl2N2
Molecular Weight
179.05
Precautions
H302, H315, H319, H335
References & Citations
[1]Hutchinson JH, et al. Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX. ACS Med Chem Lett. 2017 Mar 1;8 (4) :423-427.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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