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GPBAR-A

GPBAR-A is a specific agonist of the bile acid receptor GPBAR1. GPBAR-A can be used for the research of diabetes mellitus[1].

Product Specifications

CAS Number

[877052-79-4]

UNSPSC

12352005

Target

G protein-coupled Bile Acid Receptor 1

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gpbar-a.html

Solubility

10 mM in DMSO

Smiles

O=C1N(CC2=C(C3=C(F)C=CC=C3)C=CN=C2OC1)CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4

Molecular Formula

C23H15F7N2O2

Molecular Weight

484.37

References & Citations

[1]Parker HE, et al. Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br J Pharmacol. 2012 Jan;165 (2) :414-23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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