Antimalarial agent 44
Antimalarial agent 44 (Compound 3) is an antimalarial agent against parasite. Antimalarial agent 44 has a good permeability across MDCK-MDR1 cell monolayers and a high clearance by mouse liver microsomes[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-44.html
Smiles
O=C(C1=CC(NC(C2=NC=CC=C2)=O)=C(C=C1)OC3=CC=C(C[C@@H]4NC(OC(C)(C)C)=O)C=C3)CNC([C@H](CC5=CC=CC=C5)NC4=O)=O
Molecular Formula
C37H37N5O7
Molecular Weight
663.72
References & Citations
[1]Riu, et al. Discovery of a Series of Macrocycles as Potent Inhibitors of Leishmania Infantum. Journal of medicinal chemistry, 2024, 67 (20) :18170-18193.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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