Antimalarial agent 44

Antimalarial agent 44 (Compound 3) is an antimalarial agent against parasite. Antimalarial agent 44 has a good permeability across MDCK-MDR1 cell monolayers and a high clearance by mouse liver microsomes[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antimalarial-agent-44.html

Smiles

O=C(C1=CC(NC(C2=NC=CC=C2)=O)=C(C=C1)OC3=CC=C(C[C@@H]4NC(OC(C)(C)C)=O)C=C3)CNC([C@H](CC5=CC=CC=C5)NC4=O)=O

Molecular Formula

C37H37N5O7

Molecular Weight

663.72

References & Citations

[1]Riu, et al. Discovery of a Series of Macrocycles as Potent Inhibitors of Leishmania Infantum. Journal of medicinal chemistry, 2024, 67 (20) :18170-18193.