DXR-IN-2
Product Specifications
UNSPSC Description
DXR-IN-2 is a 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) inhibitor and an antimalarial agent (IC50: 0.1062 μM for Plasmodium falciparum DXR and 0.369 μM for Plasmodium falciparum). DXR-IN-2 inhibits Plasmodium falciparum growth by suppressing the methyl erythritol phosphate (MEP) pathway via DXR[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dxr-in-2.html
Smiles
O=C(C1=CC=CC=C1)N(C/C=C/P(O)(O)=O)O
Molecular Weight
257.18
References & Citations
[1]Wang X, et al. MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase. ACS Infect Dis. 2023, 9(7):1387-1395.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158818/DXR-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158818/
Clinical Information
No Development Reported
CAS Number
2260608-07-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1217228-01 0.02 mg (E-Coli)
Recombinant Anoxybacillus flavithermus Hydroxyethylthiazole kinase (thiM)
Ask
View Details 
MBS1217228-02 0.02 mg (Yeast)
Recombinant Anoxybacillus flavithermus Hydroxyethylthiazole kinase (thiM)
Ask
View Details 
MBS1217228-03 0.1 mg (E-Coli)
Recombinant Anoxybacillus flavithermus Hydroxyethylthiazole kinase (thiM)
Ask
View Details MBS1217228-04 0.1 mg (Yeast)
Recombinant Anoxybacillus flavithermus Hydroxyethylthiazole kinase (thiM)
Ask
View Details MBS1217228-05 0.02 mg (Baculovirus)
Recombinant Anoxybacillus flavithermus Hydroxyethylthiazole kinase (thiM)
Ask
View Details 
MBS1217228-06 0.02 mg (Mammalian-Cell)
Recombinant Anoxybacillus flavithermus Hydroxyethylthiazole kinase (thiM)
Ask
View Details