Mahanine
Mahanine is a carbazole alkaloid with various biological properties. Mahanine is a potent anticancer agent against different types of cancer cells. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection research research.
Product Specifications
CAS Number
28360-49-8
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mahanine.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
OC1=CC2=C(C3=C(N2)C4=C(C(C)=C3)O[C@@](CC/C=C(C)/C)(C)C=C4)C=C1
Molecular Formula
C23H25NO2
Molecular Weight
347.45
References & Citations
[1]Kaushik Bhattacharya, et al. Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways. Biochem Pharmacol. 2010 Feb 1;79 (3) :361-72.|[2]Saptarshi Roy, et al. Mahanine exerts in vitro and in vivo antileishmanial activity by modulation of redox homeostasis. Sci Rep
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Leishmania
Available Sizes
Frequently Asked Questions
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