MS15203
MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1].
Product Specifications
CAS Number
73912-52-4
Product Name Alternative
MS0015203
UNSPSC
12352005
Hazard Statement
H302, H319
Target
GPR171
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ms15203.html
Purity
99.40
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(C(NC1=CC(C(O)=O)=CC(C(O)=O)=C1)=O)=C
Molecular Formula
C12H11NO5
Molecular Weight
249.22
Precautions
H302, H319
References & Citations
[1]Wardman JH, et al. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Sci Signal. 2016 May 31;9 (430) :ra55.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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