MS15203

MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1].

Product Specifications

CAS Number

[73912-52-4]

Product Name Alternative

MS0015203

UNSPSC

12352005

Hazard Statement

H302, H319

Target

GPR171

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ms15203.html

Purity

99.40

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(C(NC1=CC(C(O)=O)=CC(C(O)=O)=C1)=O)=C

Molecular Formula

C12H11NO5

Molecular Weight

249.22

Precautions

H302, H319

References & Citations

[1]Wardman JH, et al. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Sci Signal. 2016 May 31;9 (430) :ra55.