HG-7-86-01
Product Specifications
UNSPSC Description
HG-7-86-01 (Compound 26) is type II tyrosine kinase inhibitor. HG-7-86-01 has anti-proliferative activity[1].
Target Antigen
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hg-7-86-01.html
Solubility
DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1CC1)NC2=NC3=CC=C(C4=CC=CC(C(NC5=CC(N6C=NC(C)=C6)=CC(C(F)(F)F)=C5)=O)=C4)N=C3S2
Molecular Weight
562.57
References & Citations
[1]Choi HG, et al. Development of 'DFG-out' inhibitors of gatekeeper mutant kinases. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5297-302.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161057/HG-7-86-01-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161057/HG-7-86-01-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1258391-14-8
Available Sizes
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