Human BMP-16 Protein, His tag (Animal-Free)

Bone morphogenetic protein 16 (BMP-16) predicts a molecular mass of 18 kDa. BMPs are multi-functional Growth Factorss that belong to the transforming Growth Factors beta (TGF-β) superfamily. BMPs initiate signaling from the cell surface by binding to two different receptors (R: Type I and II) . The heterodimeric formation of type I R and II R may occur before or after BMP binding, inducing signal transduction pathways through SMADs.

Product Specifications

Background

Bone morphogenetic protein 16 (BMP-16) predicts a molecular mass of 14 kDa. BMPs are multi-functional Growth Factorss that belong to the transforming Growth Factors beta (TGF-β) superfamily. BMPs initiate signaling from the cell surface by binding to two different receptors (R: Type I and II) . The heterodimeric formation of type I R and II R may occur before or after BMP binding, inducing signal transduction pathways through SMADs

Product Name Alternative

Bone morphogenetic protein 16, Nodal, BMP16

Gene ID

4838

Accession Number

Q96S42

Tag

BMP-16

Type

Cytokines and proteins

Applications

His tag

Purity

> 98 % as determined by SDS-PAGE

Activity

Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED₅₀ for this effect is <2.2 ng/mL.

Molecular Formula

13.75 kDa

Molecular Weight

13.75 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin :< 0.1 EU per 1 μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA,10% FBS or 0.1%BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human BMP-16 consists of 111 amino acids and predicts a molecular mass of 13.75 kDa.

Formulation

Lyophilized from sterile 20mM sodium citrate,0.2 M NaCl, pH 3.5.

Applications Notes

Human

Other Product Names

BMP16, BMP-16, BMP 16, bone morphogenetic protein 16, Nodal, BMP16

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously.