Mal-PEG4-VC-PAB-DMEA-PNU-159682
Product Specifications
UNSPSC Description
Mal-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
Target Antigen
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg4-vc-pab-dmea-pnu-159682.html
Purity
96.17
Solubility
DMSO : ≥ 50 mg/mL
Smiles
C[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCN(C)C(OCC6=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN7C(C=CC7=O)=O)=O)=O)=O)=O)C=C6)=O)=O)=O)(O)C4)C(O)=C8C(C(C9=C(OC)C=CC=C9C8=O)=O)=C5O
Molecular Weight
1559.62
References & Citations
[1]John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126687/Mal-PEG4-VC-PAB-DMEA-PNU-159682-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126687/Mal-PEG4-VC-PAB-DMEA-PNU-159682-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2259318-52-8
Available Sizes
Curated Selection
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