Machilin A
Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.
Product Specifications
CAS Number
[110269-50-6]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/machilin-a.html
Solubility
10 mM in DMSO
Smiles
C[C@H](CC1=CC=C(OCO2)C2=C1)[C@@H](C)CC3=CC=C(OCO4)C4=C3
Molecular Formula
C20H22O4
Molecular Weight
326.39
References & Citations
[1]Li G, et al.Melanin biosynthesis inhibitors from the bark of Machilus thunbergii. Biol Pharm Bull. 2003 Jul;26 (7) :1039-41.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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