3-Hydroxy agomelatine-d3
3-Hydroxy agomelatine-d3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM[1].
Product Specifications
CAS Number
1079774-23-4
UNSPSC
12352005
Target
5-HT Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.92
Solubility
10 mM in DMSO|DMSO : 250mg/mL (ultrasonic)
Smiles
CC(NCCC1=C2C=C(OC([2H])([2H])[2H])C=CC2=CC(O)=C1)=O
Molecular Formula
C15H14D3NO3
Molecular Weight
262.32
References & Citations
[1]Chagraoui A, et al. Agomelatine (S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats. Psychopharmacology (Berl) . 2003 Oct;170 (1) :17-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α-1 microglobulin
Available Sizes
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