Uniconazole

Uniconazole, a plant growth retardant, is a potent inhibitor of abscisic acid (ABA) catabolism with an IC50 of 68 nM against ABA 8’-hydroxylase. Uniconazole is a potent competitive inhibitor of CYP707A3 activity with a Ki of 8 nM. Uniconazole evidently inhibits gibberellin biosynthesis, and brassinosteroid biosynthesis is also inhibited to some extent[1].

Product Specifications

CAS Number

[83657-22-1]

UNSPSC

12352005

Hazard Statement

H302, H411

Target

Cytochrome P450; ROS Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/uniconazole.html

Concentration

10mM

Purity

98.98

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

OC(C(C)(C)C)/C(N1N=CN=C1)=C\C2=CC=C(Cl)C=C2

Molecular Formula

C15H18ClN3O

Molecular Weight

291.78

Precautions

H302, H411

References & Citations

[1]Saito S, et al. A plant growth retardant, uniconazole, is a potent inhibitor of ABA catabolism in Arabidopsis. Biosci Biotechnol Biochem. 2006 Jul;70 (7) :1731-9. |[2]Zhang M, et al. Uniconazole-induced tolerance of soybean to water deficit stress in relation to changes in photosynthesis, hormones and antioxidant system. J Plant Physiol. 2007 Jun;164 (6) :709-17.