Copper sulfate pentahydrate, 99.9%

Copper sulfate pentahydrate, 99% is a biochemical reagent. Copper sulfate pentahydrate, 99% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, 99% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, 99% is cytotoxic to various cells. Copper sulfate pentahydrate, 99% has antioxidant activity. Copper sulfate pentahydrate, 99% can be used in the research of diabetes, Parkinson's disease and DMBA (HY-W011845) -induced tumors[1][2][3][4][5][6][7].

Product Specifications

CAS Number

[7758-99-8]

UNSPSC

12352200

Hazard Statement

H302, H318, H410

Target

Biochemical Assay Reagents; Caspase; MyD88; Reactive Oxygen Species (ROS) ; SOD

Type

Biochemical Assay Reagents

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/copper-sulfate-pentahydrate-99-9.html

Purity

99.90

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=S([O-])([O-])=O.[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Cu+2]

Molecular Formula

CuH10O9S

Molecular Weight

249.69

Precautions

H302, H318, H410

References & Citations

[1]Feyzi A, et al. Copper sulfate pentahydrate reduced epithelial cytotoxicity induced by lipopolysaccharide from enterogenic bacteria. Biomed Pharmacother. 2017 May;89:454-461. |[2]Wang T, et al. Copper Nanoparticles and Copper Sulphate Induced Cytotoxicity in Hepatocyte Primary Cultures of Epinephelus coioides. PLoS One. 2016 Feb 18;11 (2) :e0149484.|[3]Chaderjian WB, et al. Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed. Biotechnol Prog. 2005 Mar-Apr;21 (2) :550-3.|[4]NAKASHIMA, K. et al.Membrane protein cross-linking is an early step in the pathogenesis of copper-induced hemolytic < /b> < b> anemia < /b> Biomedical Research, 1 (6), 548–551.|[5]Sitasawad S, et al. Beneficial effect of supplementation with copper sulfate on STZ-diabetic mice (IDDM) . Diabetes Res Clin Pract. 2001 May;52 (2) :77-84.|[6]Alcaraz-Zubeldia M, et al. Neuroprotective effect of acute and chronic administration of copper (II) sulfate against MPP+ neurotoxicity in mice. Neurochem Res. 2001 Jan;26 (1) :59-64. |[7]Burki HR, et al. Effect of oral copper sulfate on 7,12-dimethylbenz (alpha) anthracene carcinogenesis in mice. Br J Cancer. 1969 Sep;23 (3) :591-6.