Oleanolic acid
Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
Product Specifications
CAS Number
508-02-1
Product Name Alternative
Oleanic acid; Caryophyllin
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Endogenous Metabolite; HIV; MAP3K
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Oleanolic-Acid.html
Purity
98.0
Solubility
DMF : 45.45 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 5 mg/mL (ultrasonic)
Smiles
C[C@]([C@@]1([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@@](C4=CC1)(CC[C@]5(C(O)=O)[C@@]4([H])CC(C)(C)CC5)C
Molecular Formula
C30H48O3
Molecular Weight
456.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhao X, et al. Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis. Mol Cell Biochem. 2015 Feb;400 (1-2) :1-7.|[2]Liu J, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014 Nov;25 (11) :1154-60.|[3]Liu J, et al. p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid. Asian Pac J Cancer Prev. 2014;15 (11) :4519-25.|[4]Martín R, et al. Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the human disease. J Mol Cell Cardiol. 2014 Jul;72:250-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
MAP3K5/ASK1
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470352-100 1x 100 µL
CD31 / PECAM-1 (158-2B3), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470745-500 1x 500 µL
CD45 / LCA (2B11 + PD7/26), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402478-500 1x 500 µL
CD3e (T-Cell Marker) (C3e/2478), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680329-100 1x 100 µL
Small Cell Lung Cancer (SCLC) (MOC-52), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681199-100 1x 100 µL
SUMO-2 (SUMO2/1199), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040724-100 1x 100 µL
Thyroglobulin (2H11 + 6E1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details