Oleanolic acid

Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.

Product Specifications

CAS Number

[508-02-1]

Product Name Alternative

Oleanic acid; Caryophyllin

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; Endogenous Metabolite; HIV; MAP3K

Type

Natural Products

Related Pathways

Anti-infection; Autophagy; MAPK/ERK Pathway; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Oleanolic-Acid.html

Purity

98.0

Solubility

DMF : 45.45 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 5 mg/mL (ultrasonic)

Smiles

C[C@]([C@@]1([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@@](C4=CC1)(CC[C@]5(C(O)=O)[C@@]4([H])CC(C)(C)CC5)C

Molecular Formula

C30H48O3

Molecular Weight

456.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhao X, et al. Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis. Mol Cell Biochem. 2015 Feb;400 (1-2) :1-7.|[2]Liu J, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014 Nov;25 (11) :1154-60.|[3]Liu J, et al. p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid. Asian Pac J Cancer Prev. 2014;15 (11) :4519-25.|[4]Martín R, et al. Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the human disease. J Mol Cell Cardiol. 2014 Jul;72:250-62.