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(R) -Tegoprazan

(R) -Tegoprazan ((R) -CJ-12420; example 3), a benzimidazole derivative, is a potent kidney H+/K+-ATPase inhibitor with an IC50 of 98 nM of canine kidney Na+/K+-ATPase. (R) -Tegoprazan has the potential for gastrointestinal diseases research[1].

Product Specifications

CAS Number

[942195-56-4]

Product Name Alternative

(R) -CJ-12420; (R) -RQ-00000004

UNSPSC

12352005

Target

Proton Pump

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/r-tegoprazan.html

Purity

99.78

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CN(C)C(C1=CC(O[C@H]2C3=C(F)C=C(F)C=C3OCC2)=C4C(N=C(N4)C)=C1)=O

Molecular Formula

C20H19F2N3O3

Molecular Weight

387.38

References & Citations

[1]Takeshi Hanazawa, et al. Chromane Substituted Benzimidazole Derivatives. US20070142448A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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