Hydronidone
Hydronidone is an orally active pyridine derivative. Hydronidone is an inhibitor of phosphodiesterase-4 (PDE4) and cyclo-oxygenase (COX) as well as TGF-β. Hydronidone induces mitochondrial dysfunction and triggers apoptosis. Hydronidone can be used for liver fibrosis, anti-inflammation and anti-cancer study[1][2][3].
Product Specifications
CAS Number
851518-71-3
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; COX; Mitochondrial Metabolism; Phosphodiesterase (PDE) ; TGF-beta/Smad
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hydronidone.html
Purity
99.71
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=CC(C)=CN1C2=CC=C(O)C=C2
Molecular Formula
C12H11NO2
Molecular Weight
201.22
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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