UCK2 Inhibitor-1
UCK2 Inhibitor-1 (Compound 20874830-2) is a non-competitive UCK2 inhibitor with an IC50 of 4.7 µM[1].
Product Specifications
CAS Number
[902289-98-9]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/uck2-inhibitor-1.html
Concentration
10mM
Purity
96.32
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC=CC(NC(CSC2=C(CC3=CC=CC(C)=C3O4)C4=NC(C5=CC=CC=C5)=N2)=O)=C1
Molecular Formula
C27H21N3O4S
Molecular Weight
483.54
References & Citations
[1]Okesli-Armlovich A, et al. Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening. Bioorg Med Chem Lett. 2019 Sep 15;29 (18) :2559-2564.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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