Guaiazulene
Guaiazulene is a bicyclic sesquiterpene that can cross the blood-brain barrier. Guaiazulene exhibits various biological activities such as anti-inflammatory, antioxidant, hepatoprotective, antibacterial, and anti-tumor properties. Guaiazulene is also commonly used as a colorant in cosmetics. Guaiazulene shows in vitro cytotoxicity to rat neuronal cells and N2a neuroblastoma cells at high concentrations[1][2][3][4].
Product Specifications
CAS Number
[489-84-9]
UNSPSC
12352005
Hazard Statement
H302
Target
Akt; Apoptosis; Bacterial; Caspase; Fungal; mTOR; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/guaiazulene.html
Concentration
10mM
Purity
99.26
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C1=CC2=C(C)C=CC2=C(C)C=C1)C
Molecular Formula
C15H18
Molecular Weight
198.30
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
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Deaf1, CT (Deformed Epidermal Autoregulatory Factor 1 Homolog, Nuclear DEAF-1-related Transcriptional Regulator, NUDR) (Biotin) discontinued