VY-3-135
VY-3-135 is a potent, orally active, and stable ACSS2 inhibitor with an IC50 value of 44 nM. VY-3-135 is specific to ACSS2 among the AcCoA synthetase family of enzymes. VY-3-135 does not inhibit ACSS1 or ACSS3 enzymatic activity. VY-3-135 can be used for the research of breast cancer[1].
Product Specifications
CAS Number
[1824637-41-3]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Acetyl-CoA Carboxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vy-3-135.html
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CCN(C(C(C1=CC=CC=C1)(C2=CC=CC=C2)O)=N3)C4=C3C=CC(C(NC[C@@H](C)O)=O)=C4
Molecular Formula
C26H27N3O3
Molecular Weight
429.51
Precautions
H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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