(+) -Tyrphostin B44
(+) -Tyrphostin B44 (Tyrphostin AG 835) (Compound B50) is an EGRF inhibitor with antitumor activities[1].
Product Specifications
CAS Number
133550-37-5
Product Name Alternative
Tyrphostin AG 835; Tyrphostin B 50
UNSPSC
12352005
Hazard Statement
H371, H373
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plus-tyrphostin-b44.html
Purity
97.04
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N[C@H](C1=CC=CC=C1)C)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Molecular Formula
C18H16N2O3
Molecular Weight
308.34
Precautions
H371, H373
References & Citations
[1]Soto-Cruz I, et al. The tyrphostin B42 inhibits cell proliferation and HER-2 autophosphorylation in cervical carcinoma cell lines. Cancer Invest. 2008 Mar;26 (2) :136-44.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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