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(+) -Tyrphostin B44

(+) -Tyrphostin B44 (Tyrphostin AG 835) (Compound B50) is an EGRF inhibitor with antitumor activities[1].

Product Specifications

CAS Number

[133550-37-5]

Product Name Alternative

Tyrphostin AG 835; Tyrphostin B 50

UNSPSC

12352005

Hazard Statement

H371, H373

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/plus-tyrphostin-b44.html

Purity

97.04

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N[C@H](C1=CC=CC=C1)C)/C(C#N)=C/C2=CC=C(O)C(O)=C2

Molecular Formula

C18H16N2O3

Molecular Weight

308.34

Precautions

H371, H373

References & Citations

[1]Soto-Cruz I, et al. The tyrphostin B42 inhibits cell proliferation and HER-2 autophosphorylation in cervical carcinoma cell lines. Cancer Invest. 2008 Mar;26 (2) :136-44.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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