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CDK9-IN-13

Product Specifications

UNSPSC Description

CDK9-IN-13 (compound 38) is potent and selective CDK9 inhibitor, with an IC50 of [1].

Target Antigen

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk9-in-13.html

Solubility

DMSO : 2.5 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

CC(C)N1C=C(C2=CC=NC3=C2C=C(C4CCN(CC(N5CCCCC5)=O)CC4)N3)C=CC1=O

Molecular Weight

461.60

References & Citations

[1]Barlaam B, et, al. Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement. J Med Chem. 2021 Oct 28;64(20):15189-15213.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139980/CDK9-IN-13-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139980/CDK9-IN-13-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2768712-71-4

Available Sizes

Curated Selection

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