CDK9-IN-13
CDK9-IN-13 (compound 38) is potent and selective CDK9 inhibitor, with an IC50 of [1].
Product Specifications
CAS Number
[2768712-71-4]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk9-in-13.html
Purity
99.94
Solubility
DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(C)N1C=C(C2=CC=NC3=C2C=C(C4CCN(CC(N5CCCCC5)=O)CC4)N3)C=CC1=O
Molecular Formula
C27H35N5O2
Molecular Weight
461.60
References & Citations
[1]Barlaam B, et, al. Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement. J Med Chem. 2021 Oct 28;64 (20) :15189-15213.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1; CDK12; CDK2; CDK7; CDK9
Available Sizes
Curated Selection
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