M-PEG4-Boc
M-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Product Specifications
CAS Number
883554-11-8
UNSPSC
12352203
Hazard Statement
H315-H319
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg4-boc.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
COCCOCCOCCOCCC(OC(C)(C)C)=O
Molecular Formula
C14H28O6
Molecular Weight
292.37
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.|[2]Peter Madsen, et al. Protease stabilized, pegylated insulin analogues. WO2009010428A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
Frequently Asked Questions
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