M-PEG4-Boc

M-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

Product Specifications

CAS Number

[883554-11-8]

UNSPSC

12352203

Hazard Statement

H315-H319

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m-peg4-boc.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

COCCOCCOCCOCCC(OC(C)(C)C)=O

Molecular Formula

C14H28O6

Molecular Weight

292.37

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.|[2]Peter Madsen, et al. Protease stabilized, pegylated insulin analogues. WO2009010428A1.