CK-963
CK-963 is an activator for cardiac troponin (cTnC) with Ki of 11.5 μM. CK-963 exhibits activity in enhancing cardiac contractility in Sprague-Dawley rats[1].
Product Specifications
CAS Number
2851991-63-2
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ck-963.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C(C=C(C(NC(C)=N1)=O)C1=C2)=C2OCCN3CCOCC3)(NC4=CC=C(N5C[C@H](C)C[C@@H](C)C5)N=C4)=O
Molecular Formula
C27H36N6O5S
Molecular Weight
556.68
References & Citations
[1]Collibee SE, et al., Cardiac Troponin Activator CK-963 Increases Cardiac Contractility in Rats. J Med Chem. 2024 Mar 7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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