Ifinatamab deruxtecan
Ifinatamab deruxtecan (DS-7300a) is an ADC that binds an anti-B7-H3 antibody to the DNA topoisomerase I inhibitory anti-tumor drug DXd. Ifinatamab deruxtecan has antitumor activity[1].
Product Specifications
CAS Number
2484870-92-8
Product Name Alternative
DS-7300a; MABX-9001a
UNSPSC
12352203
Target
Antibody-Drug Conjugates (ADCs)
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ifinatamab-deruxtecan.html
Purity
99.29
Solubility
10 mM in DMSO
Smiles
[Ifinatamabderuxtecan]
References & Citations
[1]Katsumata L, et al. Ifinatamab deruxtecan (I-DXd), a novel B7-H3-targeting antibody-drug conjugate, demonstrates efficient payload delivery into tumor through target-dependent internalization. Cancer Research, 2023, 83 (7_Supplement) : 4891-4891.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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