Galangin

Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity.

Product Specifications

CAS Number

[548-83-4]

Product Name Alternative

Norizalpinin; 3,5,7-Trihydroxyflavone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; Cytochrome P450

Type

Natural Products

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Galangin.html

Purity

99.99

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=CC=C2)OC3=CC(O)=CC(O)=C13

Molecular Formula

C15H10O5

Molecular Weight

270.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Ciolino HP, et al. The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor. Br J Cancer. 1999 Mar;79 (9-10) :1340-6.|[2]Wen M, et al. Galangin induces autophagy through upregulation of p53 in HepG2 cells. Pharmacology. 2012;89 (5-6) :247-55.