Benzyl alcohol

Benzyl alcohol is an aromatic alcohol, a colorless liquid with a mild aromatic odor. Benzyl alcohol is an inhibitor of P450 enzyme. Benzyl alcohol mediated Toll-Like Receptor 4 to reduce the inflammatory response of liver injury in mice[1][2][3].

Product Specifications

CAS Number

[100-51-6]

Product Name Alternative

Benzenemethanol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450; Toll-like Receptor (TLR)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Benzyl-alcohol.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCC1=CC=CC=C1

Molecular Formula

C7H8O

Molecular Weight

108.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Friedlander G, et al. Benzyl alcohol increases membrane fluidity and modulates cyclic AMP synthesis in intact renal epithelial cells. Biochim Biophys Acta. 1987 Oct 2;903 (2) :341-8.|[2]Du K, et al. Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. Food Chem Toxicol. 2015 Dec;86:253-61.|[3]Cai C, et al. Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice. Hepatology. 2014 Sep;60 (3) :990-1002.