Preclamol (hydrochloride)
Preclamol hydrochloride ((-) -3-PPP hydrochloride) is a selective dopamine autoreceptor agonist. Preclamol hydrochloride has the potential for the research of schizophrenia[1][2].
Product Specifications
CAS Number
[88768-67-6]
Product Name Alternative
(-) -3-PPP (hydrochloride)
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/preclamol-hydrochloride.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCN1C[C@H](C2=CC(O)=CC=C2)CCC1.Cl
Molecular Formula
C14H22ClNO
Molecular Weight
255.78
References & Citations
[1]Seth-Olov Thorberg, et al. Large scale synthesis and absolute configuration of (-) -3-ppp, a selective dopamine autoreceptor agonist. Tetrahedron. 1985, 41 (1) : 129-139.|[2]Tamminga CA, et al. Pharmacologic properties of (-) -3PPP (preclamol) in man. J Neural Transm Gen Sect. 1992;88 (3) :165-75.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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