Salbutamol (hemisulfate)

Salbutamol (Albuterol) hemisulfate is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol hemisulfate promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol hemisulfate can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease[1][2].

Product Specifications

CAS Number

[51022-70-9]

Product Name Alternative

Albuterol (hemisulfate) ; AH-3365 (hemisulfate)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; ERK

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway; Neuronal Signaling; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Salbutamol-hemisulfate.html

Purity

98.0

Solubility

DMSO : 2 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

OC(C1=CC(CO)=C(O)C=C1)CNC(C)(C)C.O=S(O)(O)=O

Molecular Formula

C13H22NO5S0.5

Molecular Weight

288.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13 (2) :401-412.|[2]Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47 (6) :436-445.