Biotin-PEG4-amide-Alkyne
Product Specifications
UNSPSC Description
Biotin-PEG4-amide-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-amide-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-peg4-amide-alkyne.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCCOCCOCCOCCOCCC(NCC#C)=O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
Molecular Weight
528.66
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140923/Biotin-PEG4-amide-Alkyne-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140923/Biotin-PEG4-amide-Alkyne-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1006592-45-5
Available Sizes
Curated Selection
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