Sulfo-GMBS

Sulfo-GMBS is a cross-linking agent widely used in chemical modification and coupling reactions of proteins and peptides. Among the amine-sulfhydryl cross-linkers, Sulfo-GMBS generated the largest number of cross-links and covered most of the cross-links that were identified with AMAS and GMBS[1].

Product Specifications

CAS Number

[185332-92-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sulfo-gmbs.html

Concentration

10mM

Purity

98.77

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(CCCN1C(C=CC1=O)=O)ON2C(CC(S(=O)(O[Na])=O)C2=O)=O

Molecular Formula

C12H11N2NaO9S

Molecular Weight

382.28

Precautions

H315, H319, H335

References & Citations

[1]Ding YH, et al. Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers. Anal Chem. 2016 Apr 19;88 (8) :4461-9.|[2]Yue-He Ding, et al. Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers. Anal Chem. 2016 Apr 19;88 (8) :4461-9.