Amphiregulin Antibody
Product Specifications
Background
Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-alpha receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant Human Amphiregulin is an 11.3 kDa glycoprotein consisting of 98 amino acid residues.
NCBI Gene ID
374
Swiss Prot
P15514
Accession Number
P15514
Host
Rabbit
Reactivity
Human
Immunogen
Produced from sera of rabbits immunized with highly pure Recombinant Human Amphiregulin. Anti-Human Amphiregulin-specific antibody was purified by affinity chromatography employing an immobilized Human Amphiregulin matrix.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Antibody Pairs
Field of Research
Cancer, Other, Immunology, Neuroscience
Purification
Amphiregulin-specific antibody was purified by affinity chromatography employing an immobilized Human Amphiregulin matrix
Concentration
Batch dependent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=38-368
Symbol
AREG
NCBI Official Name
Amphiregulin
NCBI Organism
Homo sapiens
Other Product Names
AR, AREG, Colorectum cell-derived growth factor (CRDGF)
Tested Applications
ELISA, WB
Protein ID
P15514.2
Physical Properties
Lyophilized
CAS Number
9007-83-4
Curated Selection
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