IL-12 Antibody (biotin)
Product Specifications
Background
IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-gamma-producing Th1 cells. Recombinant Human IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (503 total amino acid residues) .
NCBI Gene ID
P35: 3592 p40: 3593
Swiss Prot
P35: P29459 p40: P29460
Accession Number
P35: P29459 p40: P29460
Host
Goat
Reactivity
Human
Immunogen
Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hIL-12. Anti-Human IL-12 specific antibody was purified by affinity chromatography and then biotinylated.
Clonality
Polyclonal
Conjugation
Biotin
Type
Primary Antibodies, Antibody Pairs
Field of Research
COVID-19, Immunology, Cancer, Stem Cell, Other
Purification
IL-12 specific antibody was purified by affinity chromatography and then biotinylated
Concentration
Batch dependent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=38-340
Symbol
IL12A , IL12B
NCBI Official Name
Interleukin 12A, interleukin 12B
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-12, NKSF, CTL Maturation Factor (TCMF), Cytotoxic Lymphocyte Maturation Factor (CLMF), TSF p35: Interleukin-12 subunit alpha, IL-12 subunit p35, IL-12A, Cytotoxic Lymphocyte Maturation Factor 35 kDa subunit (CLMF p35), NK cell Stimulating Factor Chain 1 p40: Interleukin-12 subunit beta, IL-12 subunit p40, IL-12B, CytotoxicLymphocyte Maturation Factor 40 kDa subunit (CLMF p40), NK cell Stimulating Factor Chain 2
Tested Applications
ELISA, WB
Protein ID
P29459.2, P29460.1
Physical Properties
Lyophilized
CAS Number
9007-83-4
Curated Selection
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