Eotaxin (CCL11) Antibody (biotin)

Product Specifications

Background

Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-gamma-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Murine Eotaxin is an 8.4 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

CAS Number

9007-83-4

NCBI Gene ID

20292

Swiss Prot

P48298

Accession Number

P48298

Host

Rabbit

Reactivity

Mouse

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mEotaxin. Anti-Murine Eotaxin specific antibody was purified by affinity chromatography and then biotinylated.

Clonality

Polyclonal

Conjugation

Biotin

Type

Primary Antibodies, Antibody Pairs

Field of Research

Chemokines & Cytokines, Immunology, Other

Purification

Eotaxin specific antibody was purified by affinity chromatography and then biotinylated

Concentration

Batch dependent

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.