IL-12 Antibody

Product Specifications

Background

IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-gamma-producing Th1 cells. Recombinant Murine IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (506 total amino acid residues) .

CAS Number

9007-83-4

NCBI Gene ID

P35: 16159 p40: 16160

Swiss Prot

P35: P43431 p40: P43432

Accession Number

P35: P43431 p40: P43432

Host

Rat

Reactivity

Mouse

Immunogen

Produced in Sprague Dawley rats immunized with highly pure Recombinant Murine IL-12. Anti-Murine IL-12-specific antibody was purified from cell culture by Protein G affinity chromatography.

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Antibody Pairs

Field of Research

COVID-19, Immunology, Cancer, Stem Cell, Other

Purification

IL-12-specific antibody was purified from cell culture by Protein G affinity chromatography

Concentration

Batch dependent

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.