Oxprenolol (hydrochloride)
Product Specifications
UNSPSC Description
Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/oxprenolol-hydrochloride.html
Purity
99.86
Solubility
DMSO : 250 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
OC(COC1=CC=CC=C1OCC=C)CNC(C)C.[H]Cl
Molecular Weight
301.81
References & Citations
[1]T Nagatomo, et al. Binding Characteristics of <sup>3</sup>H-dihydroalprenolol to Beta-Adrenoceptors of Rat Heart Treated With Neuraminidase. Jpn J Pharmacol. 1983 Aug;33(4):851-7.|[2]A S Manning, et al. Abrupt Withdrawal of Chronic Beta-Blockade: Adaptive Changes in Cyclic AMP and Contractility. J Mol Cell Cardiol. 1981 Nov;13(11):999-1009.|[3]Modamio P, et al. A comparative in vitro study of percutaneous penetration of β-blockers in human skin. International journal of pharmaceutics, 2000, 194(2): 249-259.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1486/Oxprenolol-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1486/Oxprenolol-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
6452-73-9
Available Sizes
Curated Selection
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