OSu-PEG4-VC-PAB-MMAE
OSu-PEG4-VC-PAB-MMAE involves in GDP-FAmP4MMAE (Monomethylauristatin E) synthesis, which is for GDP label via site-specific conjugation[1].
Product Specifications
CAS Number
[2762518-86-3]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/osu-peg4-vc-pab-mmae.html
Purity
98.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
Molecular Formula
C74H117N11O21
Molecular Weight
1496.78
Precautions
H302, H315, H319, H335
References & Citations
[1]Yang, et al. Preparation of site-specific antibody conjugates: World Intellectual Property Organization, WO2022037665[P]. 2022-02-24.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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