EBOV-IN-7
EBOV-IN-7 (compound 26) is an inhibitor of the Ebola virus EBOV with an IC50 of 2.04 μM against EBOV-GP pseudotyped virus (pEBOV) . EBOV-IN-7 has inhibitory effects on cancer cells and inhibits the EBOV-GPcl/NPC1 interaction[1].
Product Specifications
CAS Number
[68207-16-9]
UNSPSC
12352005
Target
Filovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ebov-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C(NNC1=CC=CC=C1SC2=CC(Cl)=CC=C2[N+]([O-])=O)CN3CCCC3
Molecular Formula
C18H19ClN4O3S
Molecular Weight
406.89
References & Citations
[1]Lasala F, et al. Identification of potential inhibitors of protein-protein interaction useful to fight against Ebola and other highly pathogenic viruses. Antiviral Res. 2021 Feb;186:105011.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EBOV
Curated Selection
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